Ep 592: Brain Fog, Fatigue & the Truth About Inflammation

Have you ever said, “I just don’t feel like myself anymore” — even though your labs look normal?

In this episode of the Health Fix Podcast, Dr. Jannine Krause breaks down why inflammation starts in the brain, how it drives fatigue, brain fog, cravings, hormone imbalance, and accelerated aging — and why 2026 is the year to stop suppressing symptoms and start correcting root causes.

Inflammation isn’t just a body problem.
It’s a brain health issue first.

Your brain uses 20% of your daily calories, and when inflammation is present, it shifts into defensive mode, not performance mode. That’s when clarity disappears, energy crashes, and nothing feels like it’s working anymore.

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🚨 Signs of Brain Inflammation (Even When Labs Look “Normal”)

• Brain fog after meals
• Morning stiffness lasting longer than 30 minutes
• Energy crashes or “wired but tired” feeling
• Poor recovery from exercise
• Mood and cognition fluctuations
• Low HRV or elevated resting heart rate
• Elevated CGM readings or blood sugar swings

Pattern recognition often detects inflammation long before labs do.

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⏳ Why Inflammation Makes You Feel “Old”

When inflammation stays elevated:

• Cells don’t repair efficiently
• Mitochondria produce less energy (ATP)
• Hormone signaling becomes disrupted
• Blood sugar regulation worsens
• Fat storage increases
• The brain becomes less efficient

That’s why so many people say:

“I feel inflamed, puffy, foggy, and exhausted — but nothing is technically wrong.”

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🔄 The Key Reframe

Inflammation is not the enemy.
It’s a signal.

Suppressing it without addressing the cause is like turning off a smoke alarm while the fire keeps burning.

• Acute inflammation heals
• Chronic inflammation drains energy, accelerates aging, and blocks results
• The solution is root-cause correction, not symptom suppression

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🧬 Why Brain Fog Happens (Step-by-Step)

Chronic inflammation releases pro-inflammatory cytokines (IL-6, TNF-α, IL-1β) that:

• Travel through the bloodstream
• Cross or weaken the blood–brain barrier
• Activate microglia (the brain’s immune cells)

🚨 Result: The brain shifts into protection mode, not clarity mode.

This leads to:

• Slower thinking
• Trouble focusing
• Word-finding difficulty
• Poor mental stamina

Your brain is conserving energy for survival — not performance.

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🔋 What Actually Clears Inflammatory Brain Fog

(Not suppression — regulation)

✔ Reduce inflammatory triggers (food, toxins, stress)
✔ Stabilize blood sugar
✔ Improve circulation and oxygen delivery
✔ Calm the nervous system
✔ Support mitochondrial function

When the environment improves, the brain recovers.

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🧪 How to Measure Inflammation Beyond Standard Labs

To truly assess inflammation, you must look at:

• Immune signaling: IL-6, TNF-α, IL-1β
• Metabolic stress: Insulin, A1C, HOMA-IR, TG:HDL, CGMs
• Oxidative damage: OxLDL, 8-OHdG
• Gut integrity: Zonulin, Calprotectin, Lactoferrin
• Nervous system load: HRV, S100B, GFAP
• Circulation: hsCRP, ESR, Homocysteine, Fibrinogen, ADMA

This is why people are told “everything looks normal” — while feeling anything but.

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🎧 Bottom Line

Inflammation is your body trying to protect you.
But when it becomes chronic, it quietly rewires how you feel, think, and age.

Dr. J’s Survey to help her help you in 2026 – click HERE – fill it out & enter to win a 90 minute Health Planning session with Dr. J. Note: Drawing is Jan 6th at 8a, CST. 

👉 Listen now to learn how to reduce brain inflammation so your body can finally heal.

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Podcast Transcript

Chapters

00:00 Understanding Fatigue and Inflammation
02:45 The Role of Inflammation in Aging
05:48 Brain Health and Inflammation
08:30 The Impact of Stress and Blood Sugar
11:26 Dietary Influences on Inflammation
14:24 Environmental Factors and Inflammation
17:10 Circulation and Oxygen Delivery
19:47 Addressing Trauma and Beliefs
22:43 Mitochondrial Health and Energy Production
30:24 Understanding Mitochondrial Health and Inflammation
32:50 Markers of Metabolic Stress and Inflammation
37:44 Exploring Gut Health and Inflammation
42:54 Nervous System and Inflammation
43:52 Microdosing Peptides for Health Benefits
49:41 Protomorphogens and Bioregulators in Health
52:38 Peptides for Brain Health and Cognition
58:01 Managing Inflammation for Longevity
01:00:44 Future Directions in Health and Community Engagement

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Jannine Krause (00:02.262)
junkies on this episode the health fix podcast. I’m doing another solo podcast. So you get me Dr. Janine Krauss and on this episode, I want to talk about the most I would say impactful thing you can do for your health in 2026 and beyond. What is that? Stay tuned. I’m going to tell you. So let’s get into the podcast. So one of the biggest complaints

I hear from folks is fatigue. And it stems from brain fatigue, but also can be decision fatigue. It can be just general fatigue. It could be fatigue after eating. It could be fatigue early during a workout. I mean, I could come up with many fatigue statements. And it often comes with a foggy brain. It often comes with, I’m feeling stiff in the morning. It takes me a while to kind of warm up.

also hearing about things like, you know, I just don’t feel like myself. And right now, you know, it seems like maybe the solution is supplement with hormones. Like let’s get on some bioidentical hormones and change things. But I tend to be the one who sees folks who don’t do so well in hormones. And you know, there’s not that magical response. And for many women and men too,

The biggest thing that we’re overlooking that’s kind of the biggest factor in all of aging and we’re jumping right for the fancy stuff, like the hormones, is the inflammation. Sure, I’m sure you’ve heard inflammation a hundred times over, like inflammation, inflammation, it’s everywhere. But I think what a lot of people don’t realize is,

Inflammation affects every single part of your body, but in particular it affects the brain. It alters perception of reality, it messes with your memory and your focus, and it can create a huge issue with your mood. When you don’t feel good in your brain, you’re not gonna be the best version of yourself 100 % of the time, that’s a problem. And…

Jannine Krause (02:23.404)
If we look at neurodegenerative, so conditions that degrade the nervous system, a lot of times it’s looking at like dementia, it’s looking at Parkinson’s, Alzheimer’s. Well, what’s the root of that? Inflammation. What’s the root of gaining weight? Inflammation. You know, we could tie all this back to the body trying to do a good thing to heal us and it overloads on it. And at the end of the day, inflammation is what makes us feel old. So,

what is exactly happening with this concept of feeling old? Like what is going on? So your cells aren’t repairing like they could, like they did back in the 20s, teens, when you were a little kid. And your mitochondria, so those are your factories in every single cell, are not producing enough energy. And so that will throw off hormones. And what also is gonna happen is especially when we try to adjust things,

you know, we cut calories, we work out harder, or we start trying to do some fasting and things of that nature, we might actually end up depleting some of the nutrients we need to our brain. Because your brain takes up 20 % of your calories you eat a day. It’s a highly, highly meaty organ. And what happens, and this is something that I see so commonly, and it happened to me too. And this is why I feel like…

now’s the time to kind of talk about this because my podcast previously, episode 591, I talked about kind of what I learned in 2025 about health in general and my health. And what I’m really kind of putting the pieces together on right now is like inflammation causes you to have certain behaviors. Like I never was a sweet eater before. And I hear this from a lot of women like,

You know, I never really like sweets or it’s the opposite. I never really like salty things and now I’m going after chips and I can’t stop myself. And I have this like overarching urge to just eat these things and keep running back over and over again through the kitchen. And it’s like, that’s not even me. And this is where I’m going, yes, when estrogen declines, we will crave more carbs and the body is driven to store more fat because that’s where we can store hormones.

Jannine Krause (04:45.846)
when our ovaries aren’t making them anymore. But what if there’s another thing happening here? What if part of this is the inflammation tied up in it?

You know, lot of people are like, feel puffy, I feel foggy, I feel exhausted. And they go through all the labs and like nothing comes up and they’re like, this is aging. Well, it is, but it’s because of inflammation. inflammation isn’t really the enemy. I want to make sure we know that. Like it’s a great signal. It’s something we need to start paying attention to. Where do I feel inflamed? Where do I feel puffy? Am I brain foggy? Am I achy? When? When am I tired?

Taking note of every single thing that exhausts you, including people and situations, this will give you a ton of information about what’s going on inflammatory wise in your body. And so, yes, inflammation is your body trying to protect you. And acute inflammation will heal. Like if you trip and fall and you twist your ankle, yeah, it’s gonna swell up. Yeah, that needs to happen, but it shouldn’t keep staying swollen for life, which I see for a lot of people.

that inflammation in that ankle never goes away. And now we end up with stiff ankles that are puffy and for lack of a better term, look like cankles because they don’t have the shape they used to. And we don’t want that. I don’t want that. And so the more inflamed that your body is, the more it’s going to drain your energy, especially if it gets to the brain. And this is one of the things I’m starting to realize when we talk about

you know, trauma in the body and trauma in the nervous system and, and why people wouldn’t lose weight. It’s inflammation. But why?

Jannine Krause (06:37.176)
Trauma causes inflammation. Cortisol causes inflammation. All the things that we’re describing here, I think a lot of people will talk about trauma being stuck in the body, which yes, that can happen, but why? What’s happening there? It’s keeping the inflammation process going. Your body’s on surveillance. It thinks it needs to keep healing something. And all of this, of course, accelerates aging. It blocks results. It blocks supplements. It blocks herbs. It blocks peptides. It blocks hormones from giving you

good results. So going back to the brain, it’s often the most common, but also misunderstood area of inflammation, fatigue, and brain fog. I kind of think brain fog is a toxic brain from inflammation, inflammatory markers. And you know, how’s it happening? Well,

What happens is we have these things called cytokines. They’re like messengers in the body that come from your white blood cells that say like, there’s a problem, bring in the troops, let’s fight it. And these travel through the bloodstream to go wherever they need to go. And they can cross your blood brain barrier. And it can also, they can also over time make it more leaky. So maybe you’ve heard of leaky gut as a way that things get across from the gut into your bloodstream. Leaky brain.

Another concept there. And usually most people have a leaky gut have a leaky brain. And my dad likes to joke that his brain’s leaky just in general. That’s why he forgets things. Well, yes, but also, you know, he’s 89. How much inflammation is in there? He likes to drink. How much inflammation is in there? Love sweets. Something to think about. So.

Those cytokines, those chemical messengers from our white blood cells will take the messages and they’ll go right inside your brain into something called microglia, which are little cells in your brain. They’re immune cells. And they’re gonna trigger them to go on defense.

Jannine Krause (08:49.484)
That’s a defensive state the brain gets into. It’s not a high performing state. Think of it this way, whenever you’re feeling defensive, like someone’s criticized you and you’re on defense, you go to a low vibe energy, right? You feel down about yourself. And that doesn’t help us to heal. And trauma kind of puts us in a low vibe state. I’m thinking of all the things that can affect how we specifically perform in the brain.

And if the brain’s not working right, let’s put it this way. If we take it to another level, a lot of folks are talking about rewiring the brain, I’ve mentioned it, and changing your thoughts and your processes and going from being negative to being positive and things of that nature. Why is it so hard to change how we think? Why is it hard for some people compared to others? I have to think that it…

boils down to a certain level of inflammation.

The more inflamed you are, the more inflamed triggers you have, the more things that bring in inflammation, the more your brain’s not gonna work like it should. And the clear thoughts don’t come. I’ve noticed in myself, and maybe you’ve noticed as well, if you’ve had a day where you didn’t eat that great the day before, maybe it was a holiday, the day after, you don’t feel so great. And usually when you don’t feel so great, you don’t make great decisions.

I had a period of time where I would snap pretty quickly on folks that would, you know, pressure me to do certain things, hurry up with certain things. And when I look at it, I’m going, well, it was like in the peak of being stressed. And for me, back that time, it was skipping meals and then eating a bunch at dinnertime because that was the time I could get food in. Well, if you’re not eating all day and your blood sugar’s dropping and you already have an inflamed brain, might not be a good idea.

Jannine Krause (10:48.044)
No, tout fasting, and I’ve touted it too. I think it is beneficial.

But when we’re consistently doing it and under fueling ourselves, now this could be a problem. Now, let’s go back to the brain and the brain processing. When we get the microglia all excited, like all of those little immune cells in the brain get super excited, they’re gonna slow down the processing of the brain. And they’re gonna be like telling the brain like something’s going on, something’s going on, we gotta fight it, we gotta fight it.

that slows down your thinking process, you have trouble focusing, you have trouble finding words, and your mental ability to crunch numbers or think through complex problems drops off.

Jannine Krause (11:41.528)
And this is because your brain tries to conserve energy for survival. Not clarity, not creativity, all those things. And I’ll hear this from so many folks that I’ve lost my creativity. I can’t come up with anything creative. I can’t think of new thoughts. can’t, you know, be a thought leader.

might be because your brain’s in fight or flight mode. And as I mentioned before, your brain uses about 20 % of your caloric intake. That’s wild.

but it also shows you if you are in fight or flight and your brain needs to be on point to help you in survival, of course, the like extraneous activities like being creative, coming up with new ideas, all that stuff is not gonna happen. So I hear the common term of like, have ADD, I have ADHD. And yes, these are valid conditions, but-

how much of it is also related to brain inflammation and how could we improve ADD, ADHD and maybe not rely as much on meds if we can get the inflammation down in the body.

something to think about. I’m gonna talk about some ways of course a little bit later in the podcast. Now if inflammation reduces your brain energy so the body uses something called ATP. A-T-P. Adenosine Triphosphate. That’s our like currency in the body for energy. And if the body’s needing to make extra ATP we turn on the mitochondria, the factories and all of our cells.

Jannine Krause (13:26.742)
minus of course our red blood cells, don’t have mitochondria. So if the body’s trying to get more brain energy, it’s gonna try to upregulate ATP in the brain.

If we’re inflamed, we can’t do that. And so we’ll get worn out with simple tasks. Multitasking just doesn’t happen. Decision fatigue, so decision making doesn’t happen. And literally, it’s like your brain’s running low on fuel. And this is why often after meals, like you fuel yourself up and then you’re just like, aw, like, cog down after the meal, because your body’s like, what do do with all this? I’m already inflamed, I can’t use the energy.

I see this commonly in folks with Parkinson’s. And so this is something we need to be thinking about. The other big thing is stress and little stressors throw us way over the edge. We can be more fearful than we ever were. We can be more anxious. And I hear this a lot from a lot of women. And yes, progesterone plays into this because progesterone is kind of our calm sister hormone. And for guys, this is relevant to you too. Progesterone, guys have progesterone. You guys can calm with it too.

some guys that have microdoses of progesterone to help them. But here’s the crazy thing. Like we will right go to, if I don’t handle a stressful situation well, I need to work on regulating my nervous system. Yes, that takes time. And we can do it. But also we’ll think about, I need to rewire how I think about that. Yep, also takes time. But can be super simple if you work on your beliefs. But here’s the thing, how can you get positive beliefs?

How can you change your fearful thoughts if you’re stuck in brain inflammation mode? It’s tough. At one point, not too long ago, I found myself starting to think about worst case scenario while driving. Like what if I flip my car right now? I’m driving and there’s no one on the road. It’s so weird, right? If you ever driven in Northern Wisconsin, your biggest issue is turkeys and deer. That’s it.

Jannine Krause (15:39.086)
Maybe a fox or something, but really turkeys and deer. I don’t have traffic issues, but my brain was like thinking about crazy things and So it shows you how much? Inflammation can have you in that negative thought loop thinking weird stuff that would like never happen But like worst-case scenario stuff and if you’re already a worrier things can get worse

Jannine Krause (16:01.688)
things to be thinking about. Totally pun intended here. Now, what complicates this is also blood sugar issues. And of course, most people now have connected that inflammation equals dysregulated blood sugar and too much sugar and too many carbs and this and that and other. But what I think we’re not really thinking about as a whole is that if we don’t address insulin resistance, which is very common over 35 in men and women,

then we’re not gonna get much results on other things. And I’ve learned this the hard way with hormones. I’ve tried to give hormones and we’re working on slowly working on the insulin resistance, but nothing moves. Same thing goes if you give a peptide like a GLP-1, Ters-Apetide or Semiglutide, they’re meant to work on insulin resistance. But if someone’s so dysregulated and so inflamed, we may see some issues. So we need the vitamin C there. We need some foundations there.

And we need to be looking at the whole picture of inflammation. Because one of the things I’ve seen by using terzepatide in patients, a lot of them are like, my brain is back. I can think clearly again, this is amazing. And yeah, because it’s working on that inflammation. But for the folks that aren’t getting the faster results and the brain results like that with the GLP-1s, what we’re looking at is like, okay, we’ve got other areas that are coming in that are causing inflammation.

GLP-1s are effective, but you can’t get results with them if you’re eating junk food, if you’re not sleeping enough. If you have so much coming at you in terms of stress that you haven’t dealt with, that’s a problem. And especially if there’s a lot of overload to your brain. One of the biggest factors when there’s insulin resistance is neurotransmitter balance is highly disrupted. And when that neurotransmitter balance is off, now you’re gonna have some serious issues of how you think.

Most of the time it’s looking for dopamine hits, like more sugar, more sugar, more sugar, hit that button, more sugar. That’s a problem. And your brain works off of glucose. So you need some sugar. You need it to happen.

Jannine Krause (18:20.428)
But when you have insulin resistance, you’re not getting the sugar to the brain. You’re not getting the sugar to the cells. It’s hanging out and getting stored as fat. And this is where we get a lot of that like anxiety and brain fog kind of component. A lot of where the difficulty concentrating comes in. And this is where we’ve got to think about like, okay, how do we help these neurotransmitters? Because dopamine is going to impact focus and motivation.

Acetylcholine is going to affect your memory and how you learn. Serotonin is going to affect mood and mental stability. Especially going to help you to not head towards the depressed side of things. Now, all three of those are affected when the brain is inflamed.

Like I mentioned before, leaky brain can happen when the gut gets leaky, but we can also end up with leaky brain. The more the blood sugars off for longer, the more the body’s chronically inflamed. But also, if we’ve got mold toxins, some mycotoxins, we’ve got Lyme disease coming in. We have a brain injury that happens. Or someone who’s had a history of a brain injury is more prone to leaky brain, brain inflammation.

We’re also looking at toxic food, toxic air, toxic water. And in future podcasts, I probably will talk more about water because I’m finding that even if we do our best to filter with, we have a Berkey, say we have RO, so reverse osmosis, there can still be some issues going on that we’re not able to tackle when it comes to the water. And part of it is what minerals are in the water because reverse osmosis is gonna pull a lot out. You gotta put things back in.

then also if we’re looking at just using our fridge filter is not enough. It is not enough for what’s in tap water these days. So we’ve got a lot to think about when it comes to water. So stay tuned for those podcasts in the new year. Now, the other big thing is like when we sit in fight or flight mode, the brain’s on, right? It’s trying to figure things out. It’s trying to find a solution for us. And we’re stuck in sympathetic state.

Jannine Krause (20:37.792)
Oddly enough, we want more glucose to the brain, but we divert blood away from it.

we not have more blood. We also divert the blood away from the gut, and so digestion and detox.

And so the more stressed we are, the worse digestion gets, more chance for leaky gut, the more chance for leaky brain. So I’m sure I’ve probably kind of beat a dead horse at this point now in terms of like all of the things that contribute to inflammation.

So how do we tackle this factor? We do have to look at food. Everything that you drink or eat, anything that goes in your mouth up to mints and gum, all of that stuff. We gotta look at how that impacts us. The food market in the US still has the ability to have an error of 20 % on its labels. That’s scary. So choose food that doesn’t need a label.

That’s my answer to that.

Jannine Krause (21:53.528)
Same thing goes down the lines of what’s going on with your drinks. You know, if you’re still drinking soda at this point and you’re not, I just don’t know what to say. Like yes, there’s cleaner soda brands and things like that nature, but the sugar hits pretty high. Kombuchas, you know, there are some that are better than others. It’s so important to look at what you’re drinking. And especially if you’re getting the zero calorie ones because sucralose and

a lot of the other fake sugars out there are not doing you any favors. Stevia has a synthetic side to it that isn’t so great for a lot of people. Monk fruit, you want to make sure it’s actually monk fruit. I mean, there’s some big factors you want to be thinking about here.

when you look at what you’re drinking. The other side of this, like I said, is air and water. I already talked about water. Air quality in your home is important. And it boils down to, if you have carpets, you wanna be cleaning those, deep cleaning them well. If you have rugs, getting them out, taking care of them, the lower the load of histamine producing all the dust mites and all that stuff that’s on these, the lower amount of the histamine that’s produced by those in your body, the better.

because histamine is the neurochemical that triggers an inflammatory response. So lowering histamine load is incredibly important. Checking all of your pipes, checking under your sinks, this is the great time to do that. It’s a New Year’s check. Look behind, you know, wherever you have piping and plumbing in the house, look behind your toilet. Double check that nothing is leaking. Get up in the attic, get somebody in the crawl space. If you can’t do it yourself.

so important to know if you are getting exposed to things in your home. Because these are the chronic low level inflammation producers that cause us to age fast and keep the inflammatory train going. And you can do all the things you want to right. And if your home’s toxic, well, you got a problem. Changing your air filters. They say to change them, you know, I think quarterly.

Jannine Krause (24:05.038)
Depending on where you live, would be looking at monthly, especially if you live in a very urban area. City. Now the other big thing we need to be looking at, and I’ve already mentioned stabilizing your blood sugar. Blood sugar stabilization is so important these days because I think we are designed as a society to just inflame like that. And probably because we have toxins in our environment we can’t control.

And you know, maybe we’re eating foods that we don’t get along with, which is another reason why in the beginning of the year, I always like to do a little bit of a metabolic reset where I take out the inflammatory foods. You want to know what the inflammatory foods are? Sugar, wheat, soy, dairy. And sugar, wheat, soy, dairy. We’re doing real good today. See, maybe I got a little brain inflammation I need to work on. But also with the sugar, wheat, soy, dairy.

components that really cause trouble. Sometimes folks have issues with high histamine foods. Sometimes folks have trouble with citrus fruits. How do we know what we have trouble with? We take out the things we eat the most, like eggs, high histamine, take that out, bring it back in after a month, see if you get a reaction, see if your brain gets a little foggy, see if you get tired after eating that food. Introduce a new food every 72 hours. It’s called the inflammation, the elimination diet. Now,

The other big thing is improving your circulation and oxygen delivery too.

Talk about this a lot with Chinese medicine because it’s kind of like the foundation of everything in Chinese medicine if there’s not circulation There’s not good circulation of chi energy which is ATP and in nutrients and then the circulation of blood just blood in general the vessel to get everything there we get problems and I’m noticing a lot more people are struggling with oxygen delivery to their tissues I will see they’re not anemic But they have blood cells that are like red blood cells that are heavily packed

Jannine Krause (26:06.242)
with hemoglobin to carry extra oxygen. Then I look at their carbon dioxide levels and they’re Anything under a 25 on a CO2 level in your blood, this is your comprehensive metabolic panel, that means you’re not breathing well. You’re not getting a long enough exhale to build up carbon dioxide so that you can effectively release oxygen to your tissues. This is a problem. So could your breathing be creating some inflammation in your body? Absolutely, it’s contributing. It’s not the forefront of it.

I would say for a lot of people it’s blood sugar. And this is why everyone says protein, protein, protein, protein. But I think protein is relative to your body size, what you can tolerate, what you can digest. Because if I learned anything this year in my own self, I was trying to get my body weight in protein, like my ideal body weight in protein, which is 130 grams. But I felt like crap doing it. And I tried enzymes and that’s usually my go-to with my patients. Like, let’s do some enzymes, here we do. Didn’t work, dropped it down.

around the 100, 110 level felt better. So we gotta be thinking about these things. Like I could give someone a general ballpark, but we gotta see what really works. Too many, too much of anything isn’t a good thing, right? The old adage of moderation, everything in moderation. So when we’re looking at improving circulation, I’m gonna talk a little bit about that as to how we can judge if circulation is a factor for you.

And I would venture to say that most people have some circulatory issues right now. If your hands and feet are cold, you have circulatory issues. If you’ve had a blood clot, you have circulatory issues. If you build up with fluid, if you’ve been sitting on a plane for too long and your ankles get really swollen, you have circulation issues. If at the end of the day, you have sock lines, you have circulation issues related to lymph more than it is blood flow, but lymph and circulation are synonymous.

Just the other day I was talking with a fella who has a 15 inch long clot in his leg. Didn’t have a vaccine. Was spiked. Likely. But here we have 15 inch clot in his leg. He got COVID pretty bad when it first came around in 2019, 2020 in that timeframe, in that winter. And ended up, the clot started then. He was taking…

Jannine Krause (28:32.173)
testosterone replacement therapy at the time? He was on a really high dose of it? Probably would also slow down blood flow. Something we need to think about. Hormones do slow down blood flow to an extent. That’s why they say birth control can cause blood clots. Too much of hormones can cause thick blood. We gotta watch this. A lot of clinics are overdosing their people with hormones just to try to get them to feel better. Their good intentions are just overdosing.

And I learned that the hard way long time ago. So I microdose on hormones. But we have to be thinking about how inflamed is someone before we give them hormones. Because we know that the COVID, whether it’s vaccine, whether it’s the virus, we know it causes increased clotting in folks. We know it causes increased inflammation in the arterial and the vein systems. our circulatory systems.

So we gotta be paying attention. We gotta be thinking about this moving forward. We’re in a different realm when it comes to how inflammation affects your circulation. And at the end of the day, when I look at Chinese medicine, it makes so much sense when they’re talking about individual organs. Liver chi stagnation, liver blood deficiency. What do those mean? Energy not moving through the liver well. Well, liver can’t detox. Blood deficiency.

Not enough blood going through the liver. Thick blood. Blood deficiency is thick blood to an area. You can have blood deficiency in multiple areas, not just the liver. You can also have issues with chi and blood stagnation in the Chinese world.

Regardless of how you feel about China, the point is Asian medicine makes a freaking lot of sense and on a simple term, it’s like energy not getting there and blood not getting there. What happens to an organ if it doesn’t get blood? It dies. What happens if you sit on your leg for too long and you try to stand up? It feels kind of dead, doesn’t it? Imagine that happening to certain organs of yours. So nevertheless, the idea here is to improve.

Jannine Krause (30:48.066)
the blood flow. We’ve got to do that as part of our inflammatory or anti-inflammatory process. We also really do have to start looking at the nervous systems. And yes, I mentioned trauma, but also just in general, show me a person that doesn’t have a little bit of trauma of some sort. Show me someone that doesn’t have a little bit of negative beliefs that they’ve brought up in their life of how they feel about themselves, the world, situations. The whole idea is life happening to you or for you.

Likely you’ve heard that by now. But the point is, is you were programmed from a young age to think a certain way. And then you add some media on top of that that is based on fear. And guess what happens? Total fear. Then you get an inflamed brain? Nightmare.

We don’t want that for anyone. I don’t want that for anyone. And that’s why I’m wanting to talk about this. So I already mentioned the mitochondria. I already mentioned how that impacts because a lot of folks are talking like creatine, we need creatine to help us with our muscle mass and helps with the brain and this and that. Yeah, but there are other things that can help the mitochondria even better. We have a legal peptide. So there’s research peptides, which are not considered legal and there’s legal peptides. SS31.

is a great peptide to consider to help with your mitochondria. It’s not as quick acting as something called MOTC. MOTC is not legal. That one’s a research peptide. I like MOTC better because people actually notice the result and then can see the value in taking it versus SS31 is a little slower. But the kicker with SS31, you can see the results on labs. And this is where I am a stickler about looking at

measuring your inflammation in your body. I run a lot of labs on folks when it comes to a once-over screen. And in particular, I started to do some different ones in the last year plus since seeing what’s happened with the virus de jure, the COVID, and its clotting capabilities. I’d like to look at cytokines. So interleukin-6, IL-6.

Jannine Krause (33:02.798)
tumor necrosis factor alpha, TNF alpha. So it’s like, it looks like TNF and then a little A. And then interleukin 18. Interleukin 1B, that’s a big deal. These three are major ones to help us to really see what is going on in the body when it comes to the signaling, because cytokines are signalers from your immune system telling your immune system it needs to.

And when those are high in the body, that means we’ve got a highly inflamed body in a highly inflamed immune system. And the immune system and the nervous system will play back and forth. And I see this a lot in my folks who have had high ACEs, so adverse childhood events. I’ve seen this in folks who have had brain injuries. I see this in folks who have had a lot of recent trauma. It goes back and forth, because you’ll end up with a hyper-regulated immune system.

and then there’ll be something that taxes the nervous system. Or there’ll be something that taxes the immune system, like they get a bug, know, cold or flu, then the nervous system goes on hyper alert and we see the cyclical pattern of high inflammation and then it drops in high inflammation and then it drops. I’m starting to start to be able to really track this in folks, especially since I’ve seen them for 10 plus years in my Tacoma practice. So these are some of the things you want to be looking at.

Do I have patterns of I get sick and then either my nervous system pops off or my immune system keeps me sick for longer?

We can look at metabolic stress quite easily. Fasting insulin is a great marker. Hemoglobin A1C. There’s something called the HOMAIR. What that really is is an insulin resistance marker that you can tag on to a NMR test, which is your particle testing for your cholesterol. And I like doing that one. You could do it independently too, but really, if you’re gonna test insulin resistance, you could just get a fasting insulin.

Jannine Krause (35:08.672)
I add the HOMA IR if I’m gonna be doing lipids like all cholesterol. And along those lines, if you look at your ratio from triglycerides to HDLs, you can see too, if there’s a lot of metabolic stress. Continuous glucose monitors can also help quite a bit in this case. Now there’s a ton of debate on what’s the best one out there. The one you’ll use is what I’m gonna say because it’s gonna give you consistent data over the course of time.

the first two days and the last two days not so great. So even though there are 14 days that they’re on your body, really 10 days are the ones you wanna be paying attention to because the first two, it often shows that you’re either like really high or really low. And then.

It starts to peter out a little by the last two days of use. I tend to have people use them for about a month and take about 20 days out of that month in terms of the information and eat all your favorite foods and see what happens. Put yourself into your stressful situations, see what happens. It’s eye-opening. It’s really eye-opening to use a continuous glucose monitor, so CGM is short for that. And there’s a ton of different options out there.

You could ask your doc to order one for you, the different freestyle Libre ones, and then there’s also like Stello and other ones out there. Now, another factor that was a big clue for me when I started to realize I was getting a lot more inflammation the older I got was something called 8-OH-DG, which is eight hydroxy.

Yeah, see I still have some inflammation I need to work on. But 8-OH-DG is a good marker to look at inflammation in the body, because it’s going to give you the level of oxidative stress you have going on. Another good marker of oxidative stress is the oxidized LDLs. You can run that with a cholesterol panel.

Jannine Krause (37:13.606)
core quest or something. The 808-HDG, I get that one through the NutriEval from Jenova Diagnostics. So that one is a great one. Can give you a lot of insight as to what’s going on. The lower glutathione you have in your body, the more oxidative stress you have as well. Now, a micronutrient test can tell you how much glutathione you have.

in body can also tell you about the precursors, vitamin C, vitamin E, and then alpha-lipoic, which keeps it recycling through the system. I like that almost as a better tool than just straight 8-OH-DG. So those will be some of the looks in terms of what’s going on oxidative wise and what’s oxidative damage anyway, it’s free radicals. So it’s like, I call it cell poop from the body making

ATP, so it’s energy, in the mitochondria will end up with a lot of reactive oxygen species, and those are oxidative damage. Folks who over-exercise, folks who are pushing themselves to the limits with work will also see this happen. You’ll tend to want to make sure if you’re gonna do a micronutrient test that you at least wait 48 hours between your last heavy, heavy workout and get the blood drawn, because it can be a little misleading. You can also have abnormal…

liver enzymes too, if you don’t wait that timeframe. Which leads me into inflammation in the liver. The liver enzymes will go up, especially the more fatty the liver is, the enzymes will go up. And conventional medicine’s not gonna catch a fatty liver until the liver enzymes are actually abnormal. And so there’s something called the hepatic steatosis index that you can Google and you can put in your numbers there from your labs.

You’ll need your A1C, so your hemoglobin A1C for your blood sugar, and you’ll need your AST and your ALT, liver enzymes, to be able to determine what’s going on there. So that’s a fun one. You also need your BMI, so height to body weight calculation for those. And when I say A1C, the part of it for the hepatic steatosis index is they’re looking to see, you diabetic, are you not?

Jannine Krause (39:36.566)
in that range, because it’ll ask you a yes or no question. But the hepatic steatosis index is very interesting and predictive of if you have fatty liver. The best part about this is I’ve seen tons of people this year who have used a GOP-1 microdosed and working with vitamin C and working with just overall inflammation reduction in their lifestyle and their habits and food and diet. And liver enzymes have come down, which means their liver is becoming less fatty.

That is huge. That is incredibly huge for reducing inflammation in the body. Now, because the liver and the gut are connected, we gotta talk about gut leaky stuff. So gut integrity, intestinal permeability, if you wanna talk about it the fancy term. So zonulin is a common marker for just looking at leaky gut. And one of the markers you could get, it’s an add-on to some of the specialty tests.

I tend to like to look at calprotactin, is an inflammation of the gut lining. Lactoferrin is another one. You can order those through a stool test with LabCorp. You could also do it through Quest, but you could do something called the GI map, and that’ll show those. Genova Diagnostics also has great testing where you could see that as well. Now there are some interesting ways to look at the nervous system in the brain and assess for their inflammation. Now, I’ll be straight up honest, I don’t use these tests very often.

Usually I’m going to run these if someone has a neurodegenerative condition like Parkinson’s or Alzheimer’s and they’ve come to see me or I’m going to use them for someone who’s just had a brain injury. There’s something called the S100B protein and that’s it’s kind of a generic marker but it looks for liver, brain and kidney injury and it will also show any inflammatory processes and infectious processes going on. So it’s generic.

So you don’t really know where exactly it’s coming from if it’s the liver, the brain, or the kidneys, but based on your symptoms, you can kind of figure what might be going down. Now there’s something called the GFAP, glial fibrillary acidic protein. And this is a blood-based marker, and it shows the early detection of neurodegenerative conditions and neurological injuries. So you can see if there’s been some damage with someone there.

Jannine Krause (41:56.728)
The other one there that we have now for looking if someone has an Alzheimer’s risk is something called PTAU, P-T-A-U, and that’s via LabCorp. And we can do that one as well if you’re thinking that your nervous system inflammation is now going to another level. Or if you have a family member that has it, wanna, you know, or let’s put it this way, they’ve not been fully diagnosed, but you suspect that’s a good way to kind of see, and then to look with the rest of the family members to assess.

The other, probably my most favorite one to look at for nervous system overload and like, how are you doing with tolerating life in general is the heart rate variability. I love heart rate var

iability. I’ve looked at this for years and years and different methods, but at the end of the day, if your heart rate variability is going down, it’s dipping, it’s staying down instead of like slowly going up in response to your cardiovascular workouts, you’ve got a problem. Your nervous system is tanking. And

Could it be overtraining? Sure. But could it be looking at lifestyle factors? It’s gonna be a clue something’s off. But it’s also a great marker to use to see if things are improving. And these are like watches that you can use, the aura ring, those kind of things that look at HRV. Now, if we’re looking directly in the blood to assess how inflamed are we in the vessels, fibrinogen is a great marker in the blood. High-sensity C-reactive protein, too. ESR, which is your sed rate.

can tell us like how stegase the blood. Homocysteine is a marker for the liver that tells us about circulation as well. And then there’s something called ADMA that’s also used. I don’t use that one as commonly, but wanted to mention it just that it’s out there. Now the other biggie for looking at nervous system and circulation is resting heart rate. You could check your resting heart rate and see if it goes up and watch it overnight. If it goes up consistently over time or it’s like,

It used to be in the 50s, but now it’s in the 60s, and now it’s in the 80s. You’re experiencing neuroinflammation. And that one we can see just from Fitbits. We can look at, you know, if you have a garment, if you have, you know, a whoop, any of those. We’ll tell you that. Even your Apple Watch. So you can imagine that these tests, not all of them are commonly ordered by a primary care provider or a specialist even. And so a lot of times you can just be told everything looks normal, you’re fine, but…

Jannine Krause (44:21.112)
this is why we need to dive in and we have to start asking questions. You have to ask, did you have any of those labs run? And by the way, I will have a PDF available with a summary of everything I’ve talked about today. So if you’re like, I’m driving, I can’t take these notes to know what tests I need to look at, don’t worry, I got you. And there’ll be a link in the podcast notes at drjkrausnd.com. I got you. All right, so.

Your nervous system is probably one of the main areas of inflammation. If you’ve dialed in your sugar, you’re eating clean, you’re working out, have basically a non-toxic lifestyle in terms of what you can control. And I’ll be honest, most people come to me and they’re like, doc, I’m doing all the things. And I’m like, okay, let’s see, you know, we check it off and I’m like, yeah, they kind of are doing all the things, but cortisol is kind of fueling it.

You know, when you’re going through perimenopause, you’re into menopause, you’re gonna have some metabolic dysfunction because cortisol is gonna be wonky. And then you throw in life and now we got some more wonky. This is where, when I started looking at this and I really thought about it for a minute, this is where I decided, you know what, I do think microdosing GLP-1s is useful. And that’s why I decided to do it myself too. Yes, because I wanted people to get a win with their weight, but I also was like, you know what, we have too much data.

and I’m hearing too much, you know, it’s just too much, too good. It’s too much not to say no to it, but I don’t think the high dose levels are helping anyone. I max out at five milligrams and I’ll push it on some people just to try to get a little bit more weight loss, but I want it to drop back down and I want it back down below the 2.5. 1.25, even half of that may be a sweet spot for some folks, but we don’t want to be going up and staying at the 12.5, which is the max amount.

of turzapetide for example. Now what about GLP-3s? I think they can be incredibly helpful too. I just haven’t gone there with as many people so I don’t have as much data for you. On the handful of people in my practice that have used them, it works the same as turzapetide. So I think they both are beneficial. I don’t tout semaglutide because I don’t think it has the brain inflammation capability that the other two do. So just a little thought there. Now…

Jannine Krause (46:46.254)
How else am I helping the brain? Well, for a lot of folks, I’m looking at, okay, if we microdose a little bit of, let’s say, teresapotite, but we don’t want to get a huge weight loss or we don’t want to mess with appetite too much. Or say someone has a really slow gut and they’re terrified to use a GOP1. Awesome, let’s use KPV. KPV has been around for a long time. And while it is one of the ones that…

is a little iffy to be able to use right now. If you can get a hold of it, it’s amazing. It’s part of the Clokale OW combination with the BPC157 and TP500. That’s a blend that helps with muscles, tendons, ligaments, skin, hair, all the things. What really helps with hair more than anything is the copper GHK in terms of that peptide capability.

but what Chloe is is a combination of the ones for the tendons and ligaments, the BPC and the TB 500, copper, GHQ and KPV. I love that combination. I don’t know how long it’s gonna be available for now. So what I’m gonna say is if you’re noticing that you’re inflamed but you don’t necessarily feel like you want to do a terzapatide or a retratatide, then try KPV.

It can be used with injection. There’s also nasal sprays of it. Certain companies have it. And as we’re figuring out the lay of the land in 2026 with peptides, I’ll keep you updated on where to find these sort of things. Now here’s the other kicker. If you’re like, I can’t find any of this, I don’t want to use a research peptide site, you’re in luck. A fella named Royal Lee back in…

the 1930s, so he started his companies like 1929, but in the 1930s he started developing things called PMGs, protomorphogens. What they are, are peptides. They’re a little bit more expanded than the average peptide because he’s using animal parts. So it’s really popular right now to get liver, right? An animal liver, take a cow liver supplement. Well, he created…

Jannine Krause (49:01.91)
this whole sequencing where he extracts the protomorphism so these are specific peptides from say the pituitary gland from say the adrenal gland or even from the brain of cows. Now you may be thinking my gosh Mad Cow disease is gonna be problem they test for that.

So if we’re ending up where we don’t have the access to certain peptides and we want to help with brain inflammation, looking at what’s offered by the company standard process throughout Wisconsin, Palmyra, Wisconsin have been to their facility, amazing. They’re on point. Trust the company. They’re good stuff.

Now here’s the interesting thing, they have pituitary. So pituitary is your main signaler coming down to your body. They also have hypothalamus, which is higher up from the pituitary. So that’s like mission control sends down to the pituitary, the pituitary sends to out signals to your hormones. You could use brain protomorphogens specifically for what you’re targeting. Pituitary would be helping with hormones. It would also be growth hormone.

it would also be helping with ovary signaling. If you wanted to use the pituitropin with something called OVEX, which is another version of a peptide offering, it’s called a cytosol-based type of offering from standard process, where it’s stimulating the ovaries. So you could take the pituitary and then message down to the ovaries and support that particular complex. Drenotropin, adrenals. So if you know, like my adrenals are, you know, I’m…

super jumpy when there’s a loud sound behind me, you I think my inflammation’s coming from my nervous system, I would consider putting the adrenotropin, which helps with the adrenals combined with the neurotropin, which helps with the brain, brain-adrenal connection. See if you can help support those two while you’re working on blood sugar, while you’re working on other things. I’ve used these together with GLP-1s to kind of bring the whole process in order, especially when someone has been afraid to use

Jannine Krause (51:13.942)
what’s known as the Cavinson peptides, they’re bioregulators. So there’s something called Xenolutin. It’s bio-ovary. And if we’re looking at the number and letter that go with it, it’s the A15 bioregulator. And this one’s great for rebooting the ovaries or helping someone that lost their period because of stress or someone that is going through menopause, perimenopause, and they want to kind of give as much as they can back to those ovaries to keep them producing.

hormones as much as possible, but they’re also looking at the inflammation side of things. And they haven’t, they didn’t start hormones yet. That’s something to consider. I’d also even pair these with hormones too, at a micro dose if I was gonna do it. But at the end of the day, what I’m saying here is that if our peptides go away and the bioregulators go away in 2026, we have options. Standard process, Royal Lee was on top of it in the 30s. These have been around a long time. I’ve used them for…

my entire practice and really starting to ramp them up now because I just want to make sure we have something. Now I just mentioned those. There’s ones for the liver. There’s ones for the bladder. There’s ones, I mean, you can name it, bone, every single thing, just like the, the Cavinson peptides, which are the peptides that, Vladimir Cavinson developed in the seventies in, in Russia. And we can mimic this stuff. So if it goes away, we got it.

If you go to Europe, then grab some. But here in the US, we don’t know what’s gonna happen. So that’s why I said I got you, which is why I’m gonna lead into, I’m gonna create a community to help folks work through this and kind of take some of the tidbits from Chinese medicine because a lot of the idea of protomorphogens and things of that nature came from Chinese medicine. Because the Chinese, if they felt like their heart energy was deficient, they would eat animal heart.

If they felt like their liver was deficient, that liver blood deficiency or anemia, they would eat liver.

Jannine Krause (53:18.99)
Every single organ is an option in the Chinese medicine. I’ve read, you know, all of it in the principles. And so now it’s popular to take the different organs, but the difference between organs and protomorphogens and peptides is that if you take a whole organ, your body’s got to figure out what it needs from that organ. But if you’re doing a bioregulator or you’re doing a protomorphogen, that’s more pinpointed to help you out. So there you have it there. Now,

I teased a little bit about SS31, the peptide that helps to reset the mitochondria. I think that one is a great one to pair with a terzepotide or a retratatide. If you’re up for experimenting a little more and you need like a win on some energy, MOTC is a game changer. It burns like the dickens when you inject it, but it is worth it. So we’ll be seeing a lot more of SS31 because it is a legal peptide. You can get a hold of it.

whereas MOTC, hit or miss. That’s where we’re at with the mitochondria. And I do think that if we’re gonna work on inflaming, we do need to at least support our mitochondria at least twice a year with a little bit of SS31. And if you’re really depleted, then consider trying to find a good source of MOTC. Now, when it comes to the brain and cognition,

and preventing Alzheimer’s dementia and other neurodegenerative conditions, but also getting your brain back, we have options. There are peptides called C-max and Slink that can be used with a nasal spray, but they can also be injected. We also have something called J-147, which is an oral peptide, and it enhances the mitochondria, so little factories that make ATP function in your brain. It’s pretty cool.

So it’s helping produce ATP in the brain and it’s more potent than SS 31 and other things when it comes to working because this works specifically on the brain whereas SS 31 is working on general mitochondria in the body. Now we also have something called P21 which is a little bit harder to get a hold of and it’s coming from cerebral lysine which is one of the most amazing brain boosting and focus

Jannine Krause (55:41.4)
peptides out there, but that one is pretty much only available in Europe now. And the P21 has a nasal spray delivery option, and I have founded it at a company called Peptide Sciences. Now, how long that’s gonna be available, I don’t know, but something to consider. J147 or 147, that one is hit or miss where you find it, so you gotta be really discerning on your sources.

And here’s the thing about peptide sources. You want to see their certificate of authenticity and the testing that’s been done on these things. Now, if you want to take it to another level, invest a little bit in a third party company and, or don’t invest in a third party company for testing, that’d be really expensive unless you really wanted to. But invest in an extra bottle of what you’re gonna use and send it to a third party testing company to get.

a readout on what’s in there. You can totally do that. Now here’s the thing, if the company’s already showing it to you, I would hope that they’re going to be sincere. But let’s face it, there’s lot of scammers out there and I think that’s why the FDA currently is doing what they’re doing to help protect us from scammers. So in this weird time of what do we do with peptides? Just stay very discerning.

That’s what I can say. Now, when it comes to helping your lymph and circulation as a whole, if you’re looking like, wow, I really need some help with circulation, there is a bioregulator called Vasujin. And this one may or may not be around going forward in 2026. And I don’t have really a great substitute for it in terms of a peptide, but I have awesome substitutes for it in terms of Chinese herbs like nodogenes, donkwai and other herbs that boost circulation like gingko.

So I’m not necessarily worried about this. We got other things. Same thing goes with lymph and moving lymph. There are some amazing acupressure tools. I’ve done podcasts, I’ve done presentations on them. Sweating. Number one way to open up your skin and open up that detox capability. There’s sauna bags now, there’s red light therapy pads, there’s steam showers, there’s saunas. I mean, there’s ways to sweat. If you’re not a good sweater, you can train yourself.

Jannine Krause (58:10.766)
to start sweating. Exercise, usually the most fit folks are gonna sweat the most. So things to think about. I’ve already talked about HRV in terms of monitoring your nervous system, but you can dial in HRV types of training. So conditioning training to condition your heart. And that’ll help with circulation as well. Right now it’s really hot to talk about exercise snacks. If you haven’t heard of that term, it is 30 seconds going as hard as you can, up to three times a day. So 90 seconds a day.

to challenge your heart. And there’s some really cool capabilities of how much it helps to improve your cardiovascular function. So something to think about if you’re like, I need something to boost my circulation. The other thing for circulation that I love more than anything, qigong and tai chi. There are plenty of techniques to work on your hands and fingers to get circulation to them. There’s lots of fun techniques to get lymph and blood moving. I love this.

And I love that Tai Chi has also evolved into having it’s like people who do Tai Chi workouts. Super fun. Tai Chi walking. That’s like a hot thing right now. All right. We’ve like made it into a full on fitness thing. I dig it. Because, you know, back in the day we used to see, you know, folks doing Tai Chi in the park. And we imagine like older folks doing that. And if you’re, you know, in your 40s to 60s, you know, you’re like, that’s not me. I’m going do that when I’m in my 80s and 90s.

I think there’s benefit now and we’ve kind of made it little cooler. So I love it. I love it. So.

Jannine Krause (59:45.23)
Inflammation. You can tackle it. You can eliminate it. You can manage it. And when I say eliminate it, I had to stop there for a minute because I’m like, well, can you fully eliminate it? don’t, I mean, you don’t want to because you need it for a protective capability if you hurt yourself. So I’m going to retract my statement there and go back to inflammation. We want to make sure that we regulate it well.

And we want to make sure we’re on top of it because that is the main way to counter the signs of aging as you get older. We have some really awesome tools available to us right now that are legal. And then we have some that we’re going to have to work on. Now, copper GHQ, you can get that in the mainstream. I’m going to be playing with it this year to help folks with their skin, because if you know me, I used to like to play around with

doing injections and micro-needling with platelet-rich plasma. Now I’m gonna see what we can maybe do with some copper GHQ. What’s on the horizon for peptides, and this may be something that comes out new in the next year or so, with maybe the ones that are more legal, is dermal. So applications topically with little micro-needles that you can put on in a patch to deliver the peptides versus having to do injections all the time, because let’s face it, I don’t know about you guys.

I’m a geek, I like needles. I don’t know how I’m not a drug addict, but it’s because I’ve seen that you can do beneficial stuff with them, I guess, versus the drugs. Nevertheless, if you’re not into injecting, there are things that are coming out there. I don’t think that oral peptides are as strong as the injectables. I truly believe that. Now, am I going to say that oral ones are junk? No, you’re probably just going to have like half, 50 % of your…

benefit with the exception of BPC 157 so this one if you have a leaky gut body protective complex 157 is one of the best things for leaky gut hands down I love that that one orally now that’s for your gut notice I’m not saying for tendons and ligaments shoulder injuries I’m gonna say you gotta inject to get the best effect so alright I could talk for hours on how much I love these different things and where I’ve seen benefit but

Jannine Krause (01:02:13.494)
I do think injectable is better. Nasal sprays are decent. And if you’re like, I just can’t inject myself, that’s okay. Use the oral stuff. They do work. The PMGs, the protomorphogens and the bioregulators actually work well orally, by the way. Straight peptides, which are…

are going to be the ones like the SS 31 and the terzapatides do do better injectable. All right, so what am I up to in 2026? I am looking for your input and I’d love to know if you guys are interested in a community, if you would like to hear more information on

the peptides and how you can optimize your health, reduce your inflammation and not be taking handfuls or stinking supplements. Because I am on a mission to figure out how we can lower how many things we have to take. And of course, yes, it may swap with a little bit of injections based on what I’m talking about here. And I’m trying to figure out how I can best support you guys going forward. And I’m going to switch up the podcast a little bit in 2026, where we do some trips.

And we look at spa vacays and different things of that nature to help you kind of round out how to get that neuroinflammation down. Because I truly believe that brain inflammation and neuroinflammation are some of the things that really impact our ability to think clearly when it comes to health and our ability to think clearly when it comes to being able to take care of ourselves on a foundational level.

It’s what gets us to skip meals. causes us to say, I’ll do it later. I don’t feel like I’m so tired and has us us making poor choices. So if I can impart anything in twenty twenty six, look at your inflammation, look where things are going south and work on the blood sugar component, work on the brain component and the circulation component as it relates to your entire body.

Jannine Krause (01:04:24.278)
If you’re interested in taking a survey for me to help me learn more about what you’re interes

ted in and how I can best help you using the podcast, but also some live Q and A’s, some webinars, I just really want to help and offer sound advice from someone that’s been in the field for 20, almost 20 years now, because I’m seeing so many people using AI and I think it’s great for foundational direction.

but AI hasn’t been in the field. It doesn’t know the inside out and it doesn’t know you. And so I’m looking for how I can bridge the gap between the mess that is the medical system, folks searching out their own answers to help their health, and how can I bridge that gap and help empower you to take the steps that are gonna be awesome for your health and longevity.

Thanks for listening to the Health Fix Podcast this year. And if you’ve been around for a long time, for all these years, eight years, it’s crazy to spend that long.

I can’t say thank you enough and I’m committed to keep doing this and helping bridge that gap. So if you’re open helping out, please fill out the survey and anyone who completes the survey is gonna be entered for a chance to win a 90 minute, 2026 health strategy session with me one-on-one. I’m gonna keep it open until January.

8th and then on January 9th I’m going to announce the winner. So if you’re open to helping me out, I’d really appreciate it. Thank you guys. Have a great day, whatever you’re doing.