Peptide replacement therapy isn’t just for weight loss.


In fact, one of the most powerful peptides I use has nothing to do with the scale at all and everything to do with your immune system.

You have a small gland that sits above your heart called the thymus.


It’s the largest it will ever be at birth and shrinks dramatically as you age.

In naturopathic school, we were taught that declining immune resilience is tied to this shrinking gland.

When I was dissecting cadavers, I remember searching for the thymus in folks 70+… and it was either tiny or completely absent.

Early in my career, the only solution I learned was using micro-dosed cow thymus extracts, similar to a homeopathic or an echinacea-style immune tincture.


Helpful for kids, but not always strong enough for adults.

So I kept searching.

Fast forward to 2016: whispers started circulating about a peptide derived from thymus tissue called Thymosin Alpha-1 — a compound that could support thyroid and immune health.

Around the same time, I learned about protomorphogens (PMGs)through Standard Process.

Their thyroid PMG, Thytropin, was great for lowering thyroid antibodies… but it took months to feel relief.

Thymosin Alpha-1 was different.


Women using it in 20-day cycles of subcutaneous injections noticed improved energy, focus, immunity, and metabolic function often within days.

I saw it firsthand in two women who had tried everything for their thyroid and fatigue.


Nothing had helped until Thymosin Alpha-1.

But… there was a problem.


The cost was steep ($350+ for 20 days), FDA pressure made compounding sources vanish, and “research peptide” websites were a minefield.


Eventually, I stopped recommending it.

Then GLP-1 peptides went mainstream.


And it reignited my passion for peptide medicine.

I began tracking down clean, verified sources of Thymosin Alpha-1 and I’m thrilled to say they exist, and pricing has significantly improved.

Plus there are oral dosing options now like Integrative Peptides’ Thyropept for those that aren’t into daily subcutaneous injections. 

Why Thymosin Alpha-1 Is a Game Changer…

I think of it as an immune regulator and thyroid support booster.

Many thyroid issues, even subtle ones have immune triggers.


Viruses, chronic infections, stress, long-haul illnesses… they can all spark thyroid ups and downs.

You don’t need Hashimoto’s or hypothyroidism to benefit.


If you have an immune system, this peptide can help support it, especially if you’ve struggled with:

  • reactivated mono
  • long-haul conditions
  • frequent infections
  • chronic fatigue
  • unexplained inflammation

And pairing Thymosin Alpha-1 injections or Thyropept oral capsules with Thytropin PMG may be one of the most effective combinations I’ve seen for rebooting the thyroid-immune connection.

If you’ve been on thyroid meds, tried all the versions, and still feel “off,” it may be time for a new approach, one that supports the root (your immune system), not just the symptoms.

Jannine Krause

Get back to your wild, active, vibrant self

Let’s figure out what’s accelerating your aging process…

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